Jeff Saucerman Jeff Saucerman

Associate Professor of Biomedical Engineering


Ph.D., Bioengineering, University of California, San Diego, 2005

Department of Biomedical Engineering
University of Virginia
Box 800759 Health System
Charlottesville, VA 22908

Office: Room 2111 Phone: 434-924-5095
Lab: Room 2213/2207 Phone: 434-924-1729

jsaucerman@virginia.edu

Laboratory web site

   

Research Interests

Heart function and failure are controlled by complex signaling and transcriptional networks that are just beginning to be mapped. Our lab combines computational modeling and high-throughput experiments to discover molecular networks and drugs that control cardiac remodeling and regeneration. Our experimental approaches include high-throughput microscopy and -omic profiling of primary and induced pluripotent stem cell (iPSC)-derived cardiomyocytes. Our computational approaches include large-scale regulatory network modeling and bioinformatic analysis of -omic data. Specific focus areas include:

  • cardiomyocyte hypertrophy and death
  • extra-cellular matrix remodeling by fibroblasts and macrophages
  • cardiomyocyte proliferation

Recent Publications

More Publications  |  Google Scholar Profile