B.Sc., North Dakota State University, 1974
M.Sc., University of Virginia, 1976
Ph.D., Engineering Physics, University of Virginia, 1980

Mechanical Aerospace and Nuclear Engineering
J. W. Beams Laboratory of Physics
Room 106 Mc Cormick Road
University of Virginia
Charlottesville, VA 22901

gtg@virginia.edu

Website

Research Interests

Our research centers on the development of magnetic stereotaxis and medical magnetic manipulation systems for use in neurosurgical, neuroradiological, and other clinical applications. Magnetic stereotaxis is a technique for using magnetic fields and gradients outside the patient’s head as a means of navigating an implanted device such as a drug delivery catheter or an intracerebrovascular probe for thrombosing aneurysms. An important part of this effort is the design and prototyping of novel neurosurgical instruments and technologies used in conjunction with magnetic stereotaxis or in related surgical procedures. Other research includes studies of spinal mechanics and the kinematics of the suboccipital region of the craniomandibular complex, the development of stem cell-based techniques for the treatment of Parkinson’s disease, and the development of antisense gene therapy strategies for neoplastic diseases of the central nervous system.

Recent Publications

Tucker-Schwartz JM, Gillies GT, Scanavacca M, Sosa E, Mahapatra S
Pressure-frequency sensing subxiphoid access system for use in percutaneous cardiac electrophysiology: prototype design and pilot study results.

Chen Z, Htay A, Dos Santos W, Gillies GT, Fillmore HL, Sholley MM, Broaddus WC
In vitro angiogenesis by human umbilical vein endothelial cells (HUVEC) induced by three-dimensional co-culture with glioblastoma cells.

Broaddus WC, Prabhu SS, Gillies GT, Neal J, Conrad WS, Chen ZJ, Fillmore H, Young HF
Distribution and stability of antisense phosphorothioate oligonucleotides in rodent brain following direct intraparenchymal controlled-rate infusion.

Fillmore HL, Holloway KL, Gillies GT
Cell replacement efforts to repair neuronal injury: a potential paradigm for the treatment of Parkinson's disease.

Gillies GT, Smith JH, Humphrey JA, Broaddus WC
Positive pressure infusion of therapeutic agents into brain tissues: mathematical and experimental simulations.