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Michael L. Reed

Professor of Electrical Engineering and Biomedical Engineering

Ph.D., Electrical Engineering, Stanford University, 1987

PO Box 400743
University of Virginia
Charlottesville, VA 22904-4743

reed@virginia.edu

Research Interests

Professor Reed’s research focuses on biomedical applications of microsystems and the development of new fabrication technologies for microelectromechanical systems (MEMS). Example projects include: arrays of microprobes which can pierce tissues and inject drugs and genes into cells, including both research systems and clinical devices to prevent restenosis following balloon angioplasty; arrays of microbarbs which pierce and latch to biologic tissues, for use as mechanical connectors in surgery; three-dimensional microstructure fabrication technologies based on anodic metal oxides; microfabricated electrode arrays with integrated electronics, for recording nerve cell activity; microfabricated ultrasound transducers; nanometer-scale lithography of substrates for selective patterning of biological molecules.

Selected Publications

W. Trimmer, P. Ling, C.-K. Chin, P. Orton, R. Gaugler, S. Hashmi, G. Hashmi, B. Brunett, M. L Reed, “Injection of DNA Into Plant and Animal Tissues With Micromechanical Piercing Structures,” Proceedings of the Eighth International Workshop on Micro Electro Mechanical Systems (MEMS-95), Amsterdam, January 1995, pages 111 - 115.

S. Hashmi, P. Ling, G. Hashmi, M. L. Reed, R. Gaugler, W. Trimmer, “Genetic Transformation of Nematodes Using Arrays of Micromechanical Piercing Structures,” BioTechniques 19(5), 766 - 770, 1995.

M. L. Reed, C. C. Wu, J. R. Kneller, S. Watkins, D. A. Vorp, A. Nadeem, L. E. Weiss, K. Rebello, M. Mescher, A. J. C. Smith, W. Rosenblum, M. D. Feldman, “Micromechanical Devices for Intravascular Drug Delivery,” Journal of Pharmaceutical Sciences 87(11), 1387 - 1394, 1998.

J. R. Kneller, C. C. Wu, D. A. Vorp, M. L. Reed, L. E. Weiss, H. S. Borovetz, S. Watkins, M. D. Feldman, “The Use of Microfabricated Probes to Penetrate the Internal Elastic Lamina and Intimal Hyperplasia,” Journal of Cardiovascular Diagnosis & Procedures 16(2), 37-50, 1999.

M. D. Feldman, B. Sun, B. J. Koci, C. C. Wu, J. R. Kneller, H. S. Borovetz, S. Watkins, A. Nadeem, L. E. Weiss, M. L. Reed, A. J. C. Smith, W. Rosenblum, “Stent-Based Gene Therapy,” Journal of Long-Term Effects of Medical Implants 10(1-2), 47-68, 2000.

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