James R. Brookeman
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Professor of Radiology and Biomedical Engineering
Director of Magnetic Resonance Research and Hyperpolarized Noble Gas Facility
B.Sc. (Honors), Physics, St. Andews University, Scotland, 1964
Ph.D., Physics, St. Andews University, Scotland, 1968
University of Virginia Health System, Box 170
Lee Street
Charlottesville, VA. 22908
jrb5m@virginia.edu |
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Research Interests
Our research seeks to improve methods of both two-dimensional and three-dimensional
magnetic resonance image acquisition for diagnosis and for the planning and
development of specialized radiofrequency coils for improved imaging used in
surgery. The Department of Radiology’s research laboratory is equipped with
a 1.5 Tesla whole-body MR scanner. Plans are well advanced to install a new
enhanced-gradient 1.5 Tesla MRI for improved cardiac and neurological studies
and a 3 Tesla dedicated-head MR scanner for functional brain imaging.
Since 1996 we have pursued research in Hyperpolarized Noble Gas MR as well,
employing laser-polarized Helium-3 and Xenon-129 to study lung ventilation,
virtual colonoscopy, and tissue perfusion. At this time we are investigating
a series of asthma and COPD subjects to evaluate the clinical potential of this
new lung imaging technique.
Selected Publications
J. P. Mugler, III, B. Driehuys, J. R. Brookeman, et al. MR imaging and spectroscopy
using hyperpolarized 129Xe gas: preliminary human results. Magnetic Resonance
in Medicine, 37: 809-815, 1997.
E. E. deLange, J. P. Mugler, III, J. R. Brookeman, J. Knight-Scott, et al.
Lung airspaces: MR imaging evaluation with hyperpolarized 3He gas. Radiology,
210:851-857, 1999.
PubMed listings for this faculty member
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