BS, Physics, University of Rochester, 1988
MS, Engineering Physics, University of Virginia, 1990
PhD, Biomedical Engineering, University of Virginia, 1993
Post-doc, Radiology, University of Virginia, 1994

Box 800759
University of Virginia
Charlottesville, VA 22908

fhe6b@virginia.edu

Research Interests

The general goal of my lab is to develop MRI techniques for assessing the structure, function, and perfusion of the cardiovascular system, particularly in the setting of coronary heart disease. Recent projects have included developing echo-planar MRI methods for imaging myocardial perfusion throughout the entire heart and developing displacement-encoded MRI for high-resolution measurements of intramyocardial motion. We have access to state-of-the-art whole body 1.5T scanners for human imaging studies and to a high-field 4.7T MRI scanner for imaging small animals, particularly mice. Through collaborations with cardiologists and molecular biologists, our novel MRI methods are applied to studies involving both clinical cardiology and basic cardiovascular science.

Current Projects

1. Echo-planar myocardial tagging for dobutamine stress MRI
2. High-resolution myocardial motion tracking using cine displacement-encoded cardiac MRI
3. MRI of myocardial function in post-infarct knockout mice.

Recent Publications

Zhong X, Meyer CH, Schlesinger DJ, Sheehan JP, Epstein FH, Larner JM, Benedict SH, Read PW, Sheng K, Cai J
Tracking brain motion during the cardiac cycle using spiral cine-DENSE MRI.

Anderson JD, Epstein FH, Meyer CH, Hagspiel KD, Wang H, Berr SS, Harthun NL, Weltman A, Dimaria JM, West AM, Kramer CM
Multifactorial determinants of functional capacity in peripheral arterial disease: uncoupling of calf muscle perfusion and metabolism.

Zhong X, Helm PA, Epstein FH
Balanced multipoint displacement encoding for DENSE MRI.

Gilliam AD, Epstein FH, Acton ST
Cardiac motion recovery via active trajectory field models.

Antkowiak PF, Tersey SA, Carter JD, Vandsburger MH, Nadler JL, Epstein FH, Mirmira RG
Noninvasive assessment of pancreatic beta-cell function in vivo with manganese-enhanced magnetic resonance imaging.

More Publications