B. S., Chemistry, Grinnell College, 1977
Ph.D., Physical Chemistry, Wake Forest University, 1986

MR4 Building, Room 1192
Box 800759
University of Virginia
Charlottesville, VA 22908

berr@virginia.edu

Research Interests

Our laboratory is involved with developing magnetic resonance (MR) techniques as a tool for basic biomedical research. We have developed noninvasive, non-contrast-enhanced methods for imaging blood perfusion, demonstrated to be effective in imaging blood flow to the kidneys, lungs, heart, and brain in humans. We were also the first to demonstrate the feasibility of imaging the lung using hydrogen-based MR methods.

We have also been developing micro-imaging techniques for the study of the heart and vascular system in mice and rats. This project has been particularly challenging due to the high spatial and temporal resolution requirements.

Recent Publications

Mata JF, Bozlar U, Mugler JP, Miller GW, Berr SS, Hagspiel KD
Time-resolved and high-resolution MRA in a rabbit model of pulmonary embolism at 7 T: preliminary results.

Anderson JD, Epstein FH, Meyer CH, Hagspiel KD, Wang H, Berr SS, Harthun NL, Weltman A, Dimaria JM, West AM, Kramer CM
Multifactorial determinants of functional capacity in peripheral arterial disease: uncoupling of calf muscle perfusion and metabolism.

Locke LW, Chordia MD, Zhang Y, Kundu B, Kennedy D, Landseadel J, Xiao L, Fairchild KD, Berr SS, Linden J, Pan D
A novel neutrophil-specific PET imaging agent: cFLFLFK-PEG-64Cu.

Yang Z, Linden J, Berr SS, Kron IL, Beller GA, French BA
Timing of adenosine 2A receptor stimulation relative to reperfusion has differential effects on infarct size and cardiac function as assessed in mice by MRI.

Zhang Y, Kundu B, Fairchild KD, Locke L, Berr SS, Linden J, Pan D
Synthesis of novel neutrophil-specific imaging agents for Positron Emission Tomography (PET) imaging.

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