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(Undergraduate Level)
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A year-long design project in biomedical engineering required for BME majors. Students select, formulate, and solve a design problem either for a device or system Òdesign & buildÓ project or a Òdesign of experimentÓ research project. Projects use conceptual design, skills obtained in the integrated lab, and substantial literature and patent reviews. Projects may be sponsored by BME faculty, medical doctors, and/or companies. Students may work on their own with outside team members when appropriate or with other SEAS students in integrative teams.
APMA 212, 213, 311, BIOM 201, 204, 310, 380, fourth-year standing in BME major, or instructor permission.
3
Spring Semester
Dr. Timothy Allen, Ph.D.
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(Graduate Level)
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This graduate level course introduces techniques for constructing mathematical and computational models of biological processes at many levels of organizational scale-from genome to whole-tissue. Students will rotate through several modules where they will hear lectures, read literature, and participate in discussions focused on the various modeling techniques. In each module, students will learn: (1) Which modeling techniques are best suited for addressing biological problems of different scales, (2) Quantitative characterization of biological properties (e.g., robustness), and (3) What constitutes a valid assumption and how can complex problems in biology be simplified while maintaining biological relevance. Specific modules will teach computational techniques for: 1) genome bioinformatics (e.g., genome-scale protein sequence comparisons), 2) genome network analysis (e.g., metabolic network reconstruction & analysis), 3) multi-cellular simulations (e.g., agent-based modeling of tissue patterning), 4) whole-organ analysis (e.g., finite element analysis of heart function).
BIOM 601/602--Physiology (or equivalent); one of the following courses in cellular and/or molecular biology: BIOM 204--Cell and Molecular Biology for Engineers, BIOM 706--Genetic Engineering, BIOM--823: Cell Mechanics, Adhesion, and Locomotion, BIOM 891--Molecular Bioengineering; Programming experience in Matlab; SEAS graduate student status; Knowledge of mathematical techniques, including: Partial Differential Equations, Ordinary Differential Equations, Linear Algebra; Or instructor permission.
3
Spring Semester
Dr. Jason Papin, Ph.D.
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