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The Peirce-Cottler laboratory at the University of Virginia uses a parallel approach that combines experimental models with agent-based computational models to guide new approaches in tissue engineering. We are particularly interested in the microcirculatory system and how microvascular networks structurally adapt, through active growth and remodeling. These processes are relevant to a variety of diseases and pathologies, including heart disease, peripheral limb ischemia, cancer, and diabetes.
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