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Kristina Little, B.S.
Research Interests: I am interested in mass spectrometry and proteomics. Mass spectrometry is a powerful tool used to probe the proteomes of biological samples and discover biomarkers for disease. In the future, these biomarkers will be used as early identifiers for many diseases, including heart disease and cancer. In particular, we look at microparticles, small membrane vesicles whose levels are increased in a number of diseases. One of the main difficulties with this technology is reproducibility and the reproducible identification of low-abundance proteins. Currently, I am looking at reproducibility across multiple runs and am trying to develop a model that can be used to predict protein detection. The goal is to successfully model the process and thereby optimize detections of potential biomarkers. |
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