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Downloads » Systems analysis of metabolism in the pathogenic trypanosomatid Leishmania major:

Publications:

Chavali, A.K., J.D. Whittemore, J.A. Eddy, K.T. Williams, and J.A. Papin. 2008. Systems analysis of metabolism in the pathogenic Trypanosomatid Leishmania major. Nature/EMBO Molecular Systems Biology, 4: 177. [PubMed | Abstract | Full Text | PDF]

Resources:

1. Supplementary information 1:
Additional figures (life-cycle and process of reconstruction)
Deriving the biomass equation for Leishmania major
[download]
   
2. Supplementary information 2:
In silico non-trivial lethal double gene deletion predictions
[download]
   
3. Supplementary information 3:
Dead-end metabolites according to sub-cellular localization
[download]
   
4. Supplementary information 4:
Metabolic network reconstruction (iAC560) in Microsoft Excel format
[download]
   
5. Supplementary information 5:
Metabolic network reconstruction (iAC560) in SBML format
[download]
   
6. Supplementary information 6:
Reaction map of Leishmania major
[download]
   
7. Supplementary information 7:
Metabolite abbreviations
[download]
   
8. Supplementary information 8:
Defining fatty acid composition
[download]

Computational Systems Biology Laboratory | University of Virginia, Charlottesville